Õ¬Äи£Àû

Dr Zhihong Xu

Dr Zhihong Xu

Lecturer

±Ê³ó¶ÙÌýthesis title: Stromal-tumour interaction in pancreatic cancer.ÌýFaculty of Medicine, Õ¬Äи£Àû Sydney.

Medicine & Health
School of Clinical Medicine

I obtained my PhD degree at Õ¬Äи£Àû Sydney. My research interests focus on pancreatic cancer, chronic pancreatitis and pancreatic stellate cells. I have published more than 20 peer-reviewed publications with total citations over 1500 and one book chapter,Ìý10 publications and over 1200 citations in the past five years, and an H-index of 17. I'm a co-investigator of an Ideas Grant (2020-2023) funded by Australian National Health and Medical Research Council, the chief investigator of a project founded by Tour de Cure in 2019 and a co-investigator of a 3-year project (2018-2020) funded by Avner Pancreatic Cancer Foundation.Ìý

Phone
02 8738 9197
Location
Level 4, Ingham Institute, No. 1 Campbell Street, Liverpool, NSW 2170 Australia
  • Book Chapters | 2023
    Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment', in , Wiley, pp. 942 - 950,
    Book Chapters | 2023
    Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment: Immune Cells and Immunosuppressive Functions of Carcinoma-associated Fibroblasts and Macrophages', in The Pancreas: an Integrated Textbook of Basic Science, Medicine, and Surgery, Fourth Edition, Wiley, pp. 942 - 950,
    Book Chapters | 2017
    Apte MV; Xu Z; Pirola R; Wilson JS, 2017, 'Pancreatic Stellate Cells: What do they tell us about chronic pancreatitis?', in Pancreatitis Medical and Surgical Management, John Wiley & Sons, pp. 143 - 151
  • Journal articles | 2024
    Perera CJ; Hosen SZ; Khan T; Fang H; Mekapogu AR; Xu Z; Falasca M; Chari ST; Wilson JS; Pirola R; Greening DW; Apte MV, 2024, 'Proteomic profiling of small extracellular vesicles derived from mouse pancreatic cancer and stellate cells: Role in pancreatic cancer', Proteomics, 24,
    Journal articles | 2023
    Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka V; Janetka J; Goldstein D; Pirola R; Wilson J; Apte M, 2023, 'HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis', Cancer Letters, 568,
    Journal articles | 2023
    Perera C; Greening D; Hosen SMZ; Mekapogu AR; Xu Z; Chari S; Falasca M; Wilson J; Pirola R; Apte M, 2023, 'Proteomic analysis of co-cultured human pancreatic stellate cells and cancer cell-derived exosome cargo: novel insights into signalling pathways in pancreatic cancer', Pancreatology, 23, pp. e127 - e127,
    Journal articles | 2023
    Sarkar R; Khan T; Binang H; Xu Z; Hosen SMZ; Mekapogu A; Hoehn K; Horada N; Pirola R; Wilson J; Perera C; Apte M, 2023, 'Pancreatic cancer related diabetes: impaired glucose tolerance and insulin signalling may drive progression of pancreatic intraepithelial neoplasms (PanINs)', Pancreatology, 23, pp. e143 - e143,
    Journal articles | 2023
    Sarkar R; Xu Z; Perera CJ; Apte MV, 2023, 'Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancer', Seminars in Cancer Biology, 93, pp. 114 - 122,
    Journal articles | 2023
    Waldron RT; Mishra C; Choudhary N; Xu Z; Trivedi R; Gukovskaya A; Apte MV; Pandol SJ; Lugea A, 2023, 'Tu1421 CIGARETTE SMOKING MODULATES CYCLOOXYGENASE-2 SIGNALING AND PGE2 PRODUCTION IN PANCREATIC ACINAR CELLS', Gastroenterology, 164, pp. S - 1050,
    Journal articles | 2022
    Channon LM; Tyma VM; Xu Z; Greening DW; Wilson JS; Perera CJ; Apte MV, 2022, 'Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer', Biochimica et Biophysica Acta - Reviews on Cancer, 1877, pp. 188728,
    Journal articles | 2022
    Hosen SMZ; Uddin MN; Xu Z; Buckley BJ; Perera C; Pang TCY; Mekapogu AR; Moni MA; Notta F; Gallinger S; Pirola R; Wilson J; Ranson M; Goldstein D; Apte M, 2022, 'Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU)', Frontiers in Immunology, 13,
    Journal articles | 2021
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z, 2021, 'Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma', FASEB Journal, 35,
    Journal articles | 2021
    Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker T; Corley S; Wilkins MR; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Hgf/c-met inhibition as adjuvant therapy improves outcomes in an orthotopic mouse model of pancreatic cancer', Cancers, 13, pp. 2763,
    Journal articles | 2021
    Perera CJ; Falasca M; Chari ST; Greenfield JR; Xu Z; Pirola RC; Wilson JS; Apte MV, 2021, 'Role of pancreatic stellate cell-derived exosomes in pancreatic cancer-related diabetes: A novel hypothesis', Cancers, 13, pp. 5224,
    Journal articles | 2020
    Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An Orthotopic Resectional Mouse Model of Pancreatic Cancer', Journal of Visualized Experiments,
    Journal articles | 2020
    Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An orthotopic resectional mouse model of pancreatic cancer', Journal of Visualized Experiments, 2020, pp. 1 - 13,
    Journal articles | 2020
    Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte MV, 2020, '1133 PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES.', Gastroenterology, 158, pp. S - 221,
    Journal articles | 2020
    Pothula SP; Xu Z; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting hgf/c-met axis in pancreatic cancer', International Journal of Molecular Sciences, 21, pp. 1 - 18,
    Journal articles | 2020
    Xu Z; Pang TCY; Liu AC; Pothula SP; Mekapogu AR; Perera CJ; Murakami T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 122, pp. 1486 - 1495,
    Journal articles | 2020
    Xu Z; Pothula S; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Reply letter to comments on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 123, pp. 1466,
    Journal articles | 2020
    Zhu L; Dillon DL; Xu Z; Wightman CJ; Pirola R; Wilson J; Gukovskaya A; Apte MV; Mareninova OA, 2020, 'Mo1371 INFLAMMATORY RESPONSE IN EXPERIMENTAL PANCREATITIS INDUCED BY ALCOHOL AND CIGARETTE SMOKE IS MEDIATED THROUGH ROS-STAT3-P62 SIGNALING PATHWAY', Gastroenterology, 158, pp. S - 867,
    Journal articles | 2018
    Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, '517 - World-First Identification of Circulating Pancreatic Stellate Cells in Metastatic Pancreatic Cancer', Gastroenterology, 154, pp. S - 114,
    Journal articles | 2017
    Lugea A; Gerloff A; Su HY; Xu Z; Go A; Hu C; French SW; Wilson JS; Apte MV; Waldron RT; Pandol SJ, 2017, 'The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells', Gastroenterology, 153, pp. 1674 - 1686,
    Journal articles | 2017
    Pang TCY; Xu Z; Pothula S; Becker T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2017, 'Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research', Carcinogenesis, 38, pp. 588 - 591,
    Journal articles | 2017
    Pothula SP; Xu Z; Goldstein D; Merrett N; Pirola RC; Wilson JS; Apte MV, 2017, 'Targeting the HGF/c-MET pathway: Stromal remodelling in pancreatic cancer', Oncotarget, 8, pp. 76722 - 76739,
    Journal articles | 2016
    Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Arozena AA; Adachi H; Adams CM; Adams PD; Adeli K; Adhihetty PJ; Adler SG; Agam G; Agarwal R; Aghi MK; Agnello M; Agostinis P; Aguilar PV; Aguirre-Ghiso J; Airoldi EM; Ait-Si-Ali S; Akematsu T; Akporiaye ET; Al-Rubeai M; Albaiceta GM; Albanese C; Albani D; Albert ML; Aldudo J; Algül H; Alirezaei M; Alloza I; Almasan A; Almonte-Beceril M; Alnemri ES; Alonso C; Altan-Bonnet N; Altieri DC; Alvarez S; Alvarez-Erviti L; Alves S; Amadoro G; Amano A; Amantini C; Ambrosio S; Amelio I; Amer AO; Amessou M; Amon A; An Z; Anania FA; Andersen SU; Andley UP; Andreadi CK; Andrieu-Abadie N; Anel A; Ann DK; Anoopkumar-Dukie S; Antonioli M; Aoki H; Apostolova N; Aquila S; Aquilano K; Araki K; Arama E; Aranda A; Araya J; Arcaro A; Arias E; Arimoto H; Ariosa AR; Armstrong JL; Arnould T; Arsov I; Asanuma K; Askanas V; Asselin E; Atarashi R; Atherton SS; Atkin JD; Attardi LD; Auberger P; Auburger G; Aurelian L; Autelli R; Avagliano L; Avantaggiati ML; Avrahami L; Azad N; Awale S; Bachetti T; Backer JM; Bae DH; Bae JS; Bae ON; Bae SH; Baehrecke EH; Baek SH; Baghdiguian S; Bagniewska-Zadworna A, 2016, 'Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356', Autophagy, 12, pp. 443,
    Journal articles | 2016
    Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Arozena AA; Adachi H; Adams CM; Adams PD; Adeli K; Adhihetty PJ; Adler SG; Agam G; Agarwal R; Aghi MK; Agnello M; Agostinis P; Aguilar PV; Aguirre-Ghiso J; Airoldi EM; Ait-Si-Ali S; Akematsu T; Akporiaye ET; Al-Rubeai M; Albaiceta GM; Albanese C; Albani D; Albert ML; Aldudo J; Algül H; Alirezaei M; Alloza I; Almasan A; Almonte-Beceril M; Alnemri ES; Alonso C; Altan-Bonnet N; Altieri DC; Alvarez S; Alvarez-Erviti L; Alves S; Amadoro G; Amano A; Amantini C; Ambrosio S; Amelio I; Amer AO; Amessou M; Amon A; An Z; Anania FA; Andersen SU; Andley UP; Andreadi CK; Andrieu-Abadie N; Anel A; Ann DK; Anoopkumar-Dukie S; Antonioli M; Aoki H; Apostolova N; Aquila S; Aquilano K; Araki K; Arama E; Aranda A; Araya J; Arcaro A; Arias E; Arimoto H; Ariosa AR; Armstrong JL; Arnould T; Arsov I; Asanuma K; Askanas V; Asselin E; Atarashi R; Atherton SS; Atkin JD; Attardi LD; Auberger P; Auburger G; Aurelian L; Autelli R; Avagliano L; Avantaggiati ML; Avrahami L; Azad N; Awale S; Bachetti T; Backer JM; Bae DH; Bae JS; Bae ON; Bae SH; Baehrecke EH; Baek SH; Baghdiguian S; Bagniewska-Zadworna A, 2016, 'Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)', Autophagy, 12, pp. 1 - 222,
    Journal articles | 2016
    Pothula SP; Xu Z; Goldstein D; Biankin AV; Pirola RC; Wilson JS; Apte MV, 2016, 'Hepatocyte growth factor inhibition: A novel therapeutic approach in pancreatic cancer', British Journal of Cancer, 114, pp. 269 - 280,
    Journal articles | 2016
    Pothula SP; Xu Z; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2016, 'Key role of pancreatic stellate cells in pancreatic cancer', Cancer Letters,
    Journal articles | 2015
    Ali S; Suresh R; Banerjee S; Bao B; Xu Z; Wilson J; Philip PA; Apte M; Sarkar FH, 2015, 'Contribution of microRNAs in understanding the pancreatic tumor microenvironment involving cancer associated stellate and fibroblast cells.', American Journal of Cancer Research, 5, pp. 1251 - 1264
    Journal articles | 2015
    Apte MV; Xu Z; Pothula S; Goldstein D; Pirola RC; Wilson JS, 2015, 'Pancreatic cancer: The microenvironment needs attention too!', Pancreatology, 15, pp. S32 - S38,
    Journal articles | 2015
    Lee ATK; Xu Z; Pothula SP; Patel MB; Pirola RC; Wilson JS; Apte MV, 2015, 'Alcohol and Cigarette Smoke Components Activate Human Pancreatic Stellate Cells: Implications for the Progression of Chronic Pancreatitis', Alcoholism: Clinical and Experimental Research, 39, pp. 2123 - 2133,
    Journal articles | 2014
    Patel MB; Pothula SP; Xu Z; Lee AK; Goldstein D; Pirola RC; Apte MV; Wilson JS, 2014, 'The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell-endothelial cell interactions: Anti-angiogenic implications in pancreatic cancer', Carcinogenesis, 35,
    Journal articles | 2014
    Xu Z; Pothula SP; Wilson JS; Apte MV, 2014, 'Pancreatic cancer and its stroma: A conspiracy theory', World Journal of Gastroenterology, 20, pp. 11216 - 11229,
    Journal articles | 2013
    Xu Z; Shah S; Pirola RC; Wilson J; Apte MV, 2013, 'Su1788 Pancreatic Fibrosis in Alcohol-Fed LPS Challenged Mice Is Regulated by the TLR4 Receptor', Gastroenterology, 144, pp. S - 477,
    Journal articles | 2012
    Apte M; Xu Z; Wilson J, 2012, 'Battle-scarred pancreas: Role of pancreatic stellate cells', Pancreatology, 12, pp. e4 - e4,
    Journal articles | 2011
    Arun SJ; Xu Z; Fiala-Beer E; Phillips P; Goldstein D; Biankin A; Pirola R; Wilson JS; Apte MV, 2011, 'Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer', CANCER RESEARCH, 71,
    Journal articles | 2011
    Vonlaufen A; Phillips PA; Xu ; Zhang X; Yang L; Pirola R; Wilson JS; Apte MV, 2011, 'Withdrawal of alcohol promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', Gut, 60, pp. 238 - 246,
    Journal articles | 2010
    Phillips PA; Yang L; Shulkes A; Vonlaufen A; Poljak A; Bustamante S; Warren A; Xu ; Guilhaus M; Pirola R; Apte MV; Wilson JS, 2010, 'Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion', Proceedings of the National Academy of Sciences of the United States of America, 107, pp. 17397 - 17402,
    Journal articles | 2010
    Seth D; D'Souza el-Guindy NB; Apte MV; Mari M; Dooley S; Neumann M; Haber P; Kundu S; Darwanto A; De villiers WJ; Vonlaufen A; Xu Z; Phillips P; Yang S; Goldstein D; Pirola RM; Wilson JS; Moles A; Fernandez A; Colell A; Garcia-ruiz C; Fernandez-checa JC; Meyer C; Meindl-beinker N, 2010, 'Alcohol, signaling, and ECM turnover', Alcoholism : Clinical and Experimental Research, 34, pp. 4 - 18,
    Journal articles | 2010
    Vonlaufen A; Phillips PA; Yang L; Xu Z; Fiala-Beer E; Zhang X; Pirola R; Wilson JS; Apte MV, 2010, 'Isolation of Quiescent Human Pancreatic Stellate Cells: A Promising in vitro Tool for Studies of Human Pancreatic Stellate Cell Biology', Pancreatology, 10, pp. 434 - 443,
    Journal articles | 2010
    Xu Z; Li Y; Rizos C; Xu X, 2010, 'Novel hybrid of LS-SVM and Kalman filter for GPS/INS integration', Journal of Navigation, 63, pp. 289 - 299,
    Journal articles | 2010
    Yang L; Phillips PA; Xu Z; Youkhana J; Vonlaufen A; Pirola R; Wilson J; Apte MV, 2010, 'Collagen-I Increases the Expression of Transgelin and Lumican (Regulators of Cell Migration) by Activated Pancreatic Stellate Cells', PANCREAS, 39, pp. 1358 - 1359,
    Journal articles | 2010
    Yang L; Phillips PA; Xu Z; Youkhana J; Vonlaufen A; Pirola R; Wilson J; Apte MV, 2010, 'Collagen-I increases the expression of transgelin and lumican (regulators of cell migration) by activated pancreatic stellate cells', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, pp. A14 - A15,
    Journal articles | 2009
    Phillips P; Chow MW; Vonlaufen A; Xu Z; Yang L; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Gene expression profiling of human pancreatic stellate cells and their roles in pancreatic cancer progression.', CANCER RESEARCH, 69,
    Journal articles | 2009
    Phillips P; Yang L; Vonlaufen A; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Heat shock proteins are induced during pancreatic stellate cell activation in pancreatic cancer', CANCER RESEARCH, 69,
    Journal articles | 2009
    Phillips P; Yang L; Vonlaufen A; Xu Z; Biankin AV; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'S1820 Heat Shock Proteins Are Induced During Pancreatic Stellate Cell Activation in Pancreatic Cancer', Gastroenterology, 136, pp. A - 277,
    Journal articles | 2009
    Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Guilhaus M; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic Stellate Cells Stimulate Acinar Enzyme Secretion Via the Production of Acetylcholine', PANCREAS, 38, pp. 1038 - 1039,
    Journal articles | 2009
    Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic stellate cells synthesise and secrete acetylcholine: a potential role in enzyme secretion', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24, pp. A335 - A335,
    Journal articles | 2009
    Vonlaufen A; Phillips P; Xu Z; Zhang X; Yang L; Pirola R; Wilson JS; Apte MV, 2009, 'T1835 Alcohol Withdrawal Promotes Regression of Pancreatic Fibrosis via Induction of Pancreatic Stellate Cell (PSC) Apoptosis', Gastroenterology, 136,
    Journal articles | 2009
    Xu Z; Phillips PA; Vonlaufen A; Fiala-Beer E; Yang L; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Normal Pancreatic Stellate Cells Facilitate Pancreatic Cancer Progression, Exhibit Transendothelial Migration and Accompany Cancer Cells to Distant Metastatic Sites', PANCREAS, 38, pp. 1062 - 1062,
    Journal articles | 2008
    Vonlaufen A; Xu Z; Yang L; Phillips P; Zhang X; Pirola R; Wilson JS; Apte MV, 2008, 'T1894 Abstinence Promotes Regression While Continued Alcohol Intake Promotes Persistence of LPS-Induced Pancreatic Injury in Alcohol-Fed Rats', Gastroenterology, 134, pp. A - 585,
    Journal articles | 2007
    Vonlaufen A; Xu ZH; Biankin AV; Yang L; Parker N; Pirola RC; Wilson JS; Apte MV, 2007, 'Isolation of quiescent (normal) human pancreatic stellate cells (hPSCs): A useful in vitro tool for studies of HPSc biology', Pancreas, 35, pp. 433 - 434
  • Conference Abstracts | 2023
    Perera C; Greening D; Hosen SMZ; Mekapogu AR; Xu Z; Chari S; Falasca M; Wilson J; Pirola R; Apte M, 2023, 'Proteomic analysis of co-cultured human pancreatic stellate cells and cancer cell-derived exosome cargo: novel insights into signalling pathways in pancreatic cancer', in Pancreatology, Elsevier BV, Vol. 23, pp. e127 - e127,
    Conference Abstracts | 2023
    Sarkar R; Khan T; Binang H; Xu Z; Hosen SMZ; Mekapogu A; Hoehn K; Horada N; Pirola R; Wilson J; Perera C; Apte M, 2023, 'Pancreatic cancer related diabetes: impaired glucose tolerance and insulin signalling may drive progression of pancreatic intraepithelial neoplasms (PanINs)', in Pancreatology, Elsevier BV, Vol. 23, pp. e143 - e143,
    Conference Papers | 2022
    Perera C; Hossain MJ; Mekapogu AR; Hosen SMZ; Rajan P; Xu Z; Greenfield J; Hoehn K; Horadagoda N; Chari S; Pirola R; Wilson J; Apte MV, 2022, 'Su1261: PANCREATIC CANCER-RELATED DIABETES: A HIGH FRUCTOSE DIET FED TO TRANSGENIC, KRASLSL-G12D/+; PDXCRE/+ (KC) MICE, IS ASSOCIATED WITH PANCREATIC STELLATE CELL ACTIVATION AND ACCELERATED CANCER PROGRESSION', in Gastroenterology, Elsevier BV,
    Conference Papers | 2021
    Hosen SMZ; Haar J; Xu Z; Perera C; Buckley BJ; Mekapogu AR; Pang TC; Pothula S; Ranson M; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Targeting the urokinase plasminogen activator (uPA) pathway inhibits pancreatic cancer progression', in Pancreatology, Elsevier BV, pp. S73 - S73,
    Conference Abstracts | 2021
    Hosen SMZ; Xu Z; Perera C; Mekapogu AR; Pang TCY; Goldstein D; Pirola RC; Wilson JS; Buckley BJ; Ranson M; Apte MV, 2021, 'Targeting the Urokinase Plasminogen Activator Pathway in Combination With Chemotherapy Inhibits Pancreatic Cancer Progression', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 50, pp. 1065 - 1065,
    Conference Papers | 2021
    Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka VC; Mahoney M; Janetka JW; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte MV, 2021, '184 HEPATOCYTE GROWTH FACTOR/ C-MET PATHWAY INHIBITION COMBINED WITH CHEMOTHERAPY RETARDS PRECURSOR PANINS AND POTENTIATES LOCAL IMMUNITY IN A TRANSGENIC MODEL OF EARLY PANCREATIC CANCER', in Gastroenterology, Elsevier BV, pp. S - 45,
    Conference Papers | 2020
    Mekapogu A; Xu Z; Pothula S; Perera C; Pang T; Hosen Z; Janetka J; Damalanka V; Mahoney M; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Inhibition of both the ligand and receptor of the hepatocyte growth factor/c-MET pathway, in combination with chemotherapy, retards progression of PanIN lesions in KPC mice', in Pancreatology, Elsevier BV, pp. S39 - S40,
    Conference Abstracts | 2020
    Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Cohen-Hyams T; Killingsworth M; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Effects of pancreatic stellate cell- and cancer cell-derived exosomes on islet cell functions: Implications for pancreatic cancer-related diabetes', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, Vol. 35, pp. 23 - 23,
    Conference Papers | 2020
    Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'I. Pancreatic Stellate Cell and Cancer Cell Derived Exosomes Impair Beta Cell Function: Implications for Pancreatic Cancer Related Diabetes', in Gastroenterology, Elsevier, Chicago, USA, presented at Digestive Disease Week, Chicago, USA, 02 May 2020,
    Conference Papers | 2020
    Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Pancreatic cancer-related diabetes: Do pancreatic stellate cell and cancer cell derived exosomes play a role?', in Pancreratology, presented at European Pancreatic Club
    Conference Papers | 2020
    Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte MV, 2020, 'PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, TX, Austin, pp. S221 - S221, presented at Crohn's and Colitis Congress, TX, Austin, 23 January 2020 - 25 January 2020,
    Conference Papers | 2019
    Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of Hepatocyte Growth Factor (HGF) Signaling Pathway in Combination With Chemotherapy Reduces Tumour Burden in an Orthotopic Model of Advanced Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1551 - 1551,
    Conference Papers | 2019
    Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of hepatocyte growth factor signaling pathway in combination with chemotherapy reduces tumor burden in an orthotopic model of advanced pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 37 - 38,
    Conference Papers | 2018
    Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, 'WORLD-FIRST IDENTIFICATION OF CIRCULATING PANCREATIC STELLATE CELLS IN METASTATIC PANCREATIC CANCER', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. S114 - S114, presented at Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, DC, Washington, 02 June 2018 - 05 June 2018,
    Conference Papers | 2018
    Wilson J; Pang T; Xu Z; Mekapogu A; Pothula S; Goldstein D; Pirola R; Wilson J; Apte M, 2018, 'Establishment of a noval adjuvant model of orthotopic pancreatic cancer: effects of HGF-cMET inhibition on disease progression', Sydney, presented at Avner Cancer Symposium, Sydney
    Conference Papers | 2018
    Xu Z; Buckley BJ; Pothula S; Pang T; Goldstein D; Pirola RC; Wilson JS; Kelso MJ; Ranson M; Apte MV, 2018, 'Amiloride Analogues as Inhibitors of Human Urokinase Plasminogen Activator and Anti-Pancreatic Cancer Agents', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1434 - 1434,
    Conference Papers | 2018
    Xu Z; Pothula S; Pang T; Mekapogu A; Goldstein D; Pirola R; Wilson J; Apte M, 2018, 'Inhbition of hepatocyte growth factor (HGF) signalling pathway in combination with chemotherapy reduces tumour buden in an orthotopic pancreatic cancer model', Sydney, presented at Avner Cancer Symposium, Sydney
    Conference Papers | 2017
    Pang T; Pothula S; Xu Z; Becker T; Goldstein D; Pirola R; Wilson J; Apte M, 2017, 'Circulating tumor and stellate cells in pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 61 - 62,
    Conference Papers | 2017
    Pang T; Xu Z; Pothula S; Becker T; Goldstein D; Pirola R; Wilson J; Apte M, 2017, 'Circulating Pancreatic Stellate Cells (Cpscs) and Tumor Cells (Ctcs) in Metastatic Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1425 - 1425,
    Conference Papers | 2017
    Pothula S; Xu Z; Goldstein D; Pirola R; Wilson J; Apte M, 2017, 'Stromal reprogramming offers a novel therapeutic approach in pancreatic cancer: Implications of targeting HGF/c-MET pathway', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 62 - 62,
    Conference Papers | 2017
    Xu Z; Pothula S; Lee A; Tran D; Pandol S; Pirola R; Wilson JS; Apte M, 2017, 'Smoking worsens the fibrosis of alcoholic chronic pancreatitis via activation of pancreatic stellate cells', in Journal of Gastroenterology and Hepatology, Wiley, Gold Coast, presented at Australian Gastroenterological Week, Gold Coast, 19 August 2017 - 22 August 2017
    Conference Papers | 2017
    Xu Z; Pothula S; Lee A; Tran D; Pandol S; Pirola R; Wilson JS; Apte M, 2017, 'Smoking worsens the fibrosis of alcoholic chronic pancreatitis via activation of pancreatic stellate cells', in Pancreatology, Elsevier, Buenos Aires, presented at Joint Meeting of the International Association of Pancreatology and the 21st Meeting Latin American Pancreatic Study Group, Buenos Aires, -
    Conference Papers | 2016
    Apte M; Xu Z; Pothula S; Goldstein D; Pirola R; Wilson JS, 2016, 'Stromal remodeling in pancreatic cancer', in Pancreatology, Elsevier, Sendai, pp. S28 - S28, presented at International Association of Pancreatology, Sendai, -
    Conference Papers | 2016
    Apte M; Xu Z; Pothula S; Pirola R; Wilson JS, 2016, 'Alcohol, smoking and pancreas', in Pancreatology, Sendai, pp. S34 - S34, presented at International Association of Pancreatology, Sendai, -
    Conference Papers | 2015
    Apte M; Xu Z; Lee A; Pothula S; Pirola R; Wilson JS, 2015, 'Pancreatic stellate cells are activated by cigarette smoke components and alcohol', Toledo, Pancreatology 15(3):S10, presented at European Pancreatic Club, Toledo, Pancreatology 15(3):S10, -
    Conference Papers | 2015
    Pothula S; Xu Z; Goldstein D; Pirola R; Wilson JS; Apte M, 2015, 'Pancreatic cancer: stromal reprogramming offers a novel therapeutic approach', San Diego, Pancreas 44(8):1407, presented at American Pancreatic Association, San Diego, Pancreas 44(8):1407, -
    Conference Papers | 2015
    Pothula S; Xu Z; Goldstein D; Pirola R; Wilson JS; Apte M, 2015, 'Pancreatic cancer: stromal reprogramming offers a novel therapeutic approach', Shanghai, Pancreatology, presented at International Association of Pancreatology, Shanghai, Pancreatology, -
    Conference Papers | 2015
    Pothula S; Xu Z; Goldstein D; Pirola R; Wilson JS; Apte M, 2015, 'Pancreatic cancer: stromal reprogramming offers a novel therapeutic approach', Toledo, Pancreatology 15(3):S17, presented at European Pancreatic Club, Toledo, Pancreatology 15(3):S17, -
    Conference Papers | 2015
    Stimming EF; Rui YN; Xu Z; Chen Z; Chen D; Sun Y; Tito A; Zhang S, 2015, 'Determining Huntingtin's endogenous functions using drosophila and mammalian systems', in MOVEMENT DISORDERS, WILEY-BLACKWELL, CA, San Diego, pp. S532 - S532, presented at 19th International Congress of Parkinson's Disease and Movement Disorders, CA, San Diego, 14 June 2015 - 18 June 2015,
    Conference Papers | 2015
    Xu Z; Pothula S; Pandol S; Pirola R; Wilson JS; Apte M, 2015, 'Smoking worsens the fibrosis of alcoholic chronic pancreatitis via activation of pancreatic stellate cells', in Pancreatology, Shanghai, pp. S20 - S20, presented at International Association of Pancreatology, Shanghai, -
    Conference Papers | 2015
    Xu Z; Pothula S; Pandol S; Pirola R; Wilson JS; Apte M, 2015, 'Smoking worsens the fibrosis of alcoholic chronic pancreatitis via activation of pancreatic stellate cells', San Diego, Pancreas 44(8):1426, presented at American Pancreatic Association, San Diego, Pancreas 44(8):1426, -
    Conference Papers | 2014
    Lee A; Xu Z; Pothula S; Patel M; Pirola R; Wilson JS; Apte M, 2014, 'The influence of alcohol and cigarette smoke components on pancreatic stellate cell activation: implications for the progression of chronic pancreatitis', Southampton, Pancreatology 14(3):S9, presented at International Association of Pancreatology and European Pancreatic Club, Southampton, Pancreatology 14(3):S9, -
    Conference Papers | 2014
    Pothula S; Patel M; Xu Z; Lee A; Goldstein D; Pirola R; Apte M; Wilson JS, 2014, 'The role of hepatocyte growth factor/c-MET pathway in pancreatic stellate cell-endothelial cell interactions: anti-angiogenic implications in pancreatic cancer', Southampton, Pancreatology 14(3):S9, presented at International Association of Pancreatology and European Pancreatic Club, Southampton, Pancreatology 14(3):S9, -
    Conference Papers | 2014
    Pothula S; Xu Z; Goldstein D; Pirola R; Wilson JS; Apte M, 2014, 'Hepatocyte Growth Factor (HGF) inhibition may be a superior therapeutic approach than gemcitabine in pancreatic cancer', Melbourne, presented at Australasian Pancreatic Club and the Australian Health and Medical Research Congress, Melbourne, -
    Conference Papers | 2013
    Pothula S; Xu Z; Arun S; Goldstein D; Biankin A; Pirola R; Wilson J; Apte M, 2013, 'Hepatocyte Growth Factor Inhibition: A Therapeutic Approach Superior to Gemcitabine in Pancreatic Cancer?', in Pancreas, Lippincott Williams & Wilkins, Miami, pp. 1377 - 1377, presented at American Pancreatic Association, Miami, 31 October 2013 - 02 November 2013,
    Conference Papers | 2013
    Xu Z; Shah S; Pirola R; Wilson JS; Apte M, 2013, 'Pancreatic fibrosis in alcohol-fed LPS challenged mice is regulated by the TLR4 receptor', in Gastroenterology, Elsevier, USA, pp. S477 - S477, presented at American Gastroenterological Association, USA, -
    Conference Papers | 2013
    Xu Z; Yu X; Feng Y; Hu J; Tari Z; Han F, 2013, 'A multi-module anomaly detection scheme based on system call prediction', in Proceedings of the 2013 IEEE 8th Conference on Industrial Electronics and Applications, ICIEA 2013, pp. 1376 - 1381,
    Conference Papers | 2012
    Zhang J; Zhu L; Wang J; Mao J; Xu Z; Jiang C; Di P, 2012, 'An efficient parallel implementation for three-dimensional incompressible pipe flow based on SIMPLE', in Proceedings - 12th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, CCGrid 2012, Ottawa, Ontario, pp. 660 Article no.6217479 - 667, presented at 12th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, CCGrid 2012, Ottawa, Ontario, 13 May 2012 - 16 May 2012,
    Conference Papers | 2011
    Arun SJ; Xu Z; Fiala-Beer E; Yang L; Phillips P; Goldstein D; Biankin A; Pirola R; Wilson JS; Apte MV, 2011, 'Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer', in Journal of Gastroenterology and Hepatology, Wiley, pp. 20 - 20,
    Conference Papers | 2011
    Arun SJ; Xu Z; Fiala-Beer E; Yang L; Phillips P; Goldstein D; Biankin AV; Pirola RM; Wilson JS; Apte MV, 2011, 'Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 1310 - 1311, presented at American Pancreatic Association, Chicago USA
    Conference Papers | 2011
    Youkhana J; Liu J; Kiriella N; Yang L; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson J; Apte MV; Phillips PA, 2011, 'Heat Shock Proteins 27 and 47 Inhibit Platelet-Derived Growth Factor (PDGF)-Induced Pancreatic Stellate Cell Proliferation: Implication in Pancreatic Cancer Progression', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1365 - 1366,
    Conference Papers | 2011
    Youkhana J; Liu J; Kiriella N; Yang S; Xu Z; Biankin AV; Goldstein D; Wilson JS; Apte MV; Phillips P, 2011, 'Heat shock proteins 27 and 47 inhibit platelet-derived growth factor (PDGF)-induced pancreatic stellate cell proliferation: implication in pancreatic cancer progression', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. 19 - 19, presented at Australian Gastroenterology Week, Brisbane Australia
    Conference Papers | 2010
    Bai XJ; Ge JJ; Yang M; Du J; You B; Zhang W; Hu A; Xu Z; Zhou SM; Zheng RK, 2010, 'Inverse and normal tunneling magnetoresistance effects in FeCoGd/FeCo/AlO/FeCo multilayers', in Journal of Physics: Conference Series,
    Conference Papers | 2010
    Fiala-Beer E; Xu Z; Phillips P; Yang L; Goldstein D; Pirola R; Wilson J; Apte M, 2010, 'Role of Pancreatic Stellate Cells in Pancreatic Cancer: The Urokinase Plasminogen Activator System', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1320 - 1320,
    Conference Papers | 2010
    Fiala-Beer E; Xu Z; Phillips PA; Yang L; Goldstein D; Pirola R; Wilson JS; Apte MV, 2010, 'Role of pancreatic stellate cells in pancreatic cancer: the urokinase plasminogen system', in Journal of Gastroenterology and Hepatology, Wiley, pp. A75 - A75,
    Conference Papers | 2010
    Vonlaufen A; Phillips PA; Xu Z; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2010, 'Alcohol withdrawal promotes regression of pancreatic fibrosis via induction of pancreatic stellate cell (PSC) apoptosis', in Swiss Medical Weekly, EMH Schweizerischer Arzteverlag, pp. 12S - 12S,
    Conference Papers | 2009
    Phillips P; Yang L; Vonlaufen A; Xu Z; Biankin AV; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Heat Shock Proteins Are Induced During Pancreatic Stellate Cell Activation in Pancreatic Cancer', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. A277 - A277, presented at Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, IL, Chicago, 30 May 2009 - 04 June 2009,
    Conference Papers | 2009
    Phillips PA; Yang L; Vonlaufen A; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Heat shock proteins are induced during pancreatic stellate cell activation in pancreatic cancer', in Journal of Gastroenterology and Hepatology, Wiley, pp. A334 - A334,
    Conference Papers | 2009
    Vonlaufen A; Phillips P; Xu Z; Zhang X; Yang L; Pirola R; Wilson JS; Apte MV, 2009, 'Alcohol Withdrawal Promotes Regression of Pancreatic Fibrosis via Induction of Pancreatic Stellate Cell (PSC) Apoptosis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. A589 - A590, presented at Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, IL, Chicago, 30 May 2009 - 04 June 2009,
    Conference Papers | 2009
    Vonlaufen A; Phillips PA; Xu Z; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2009, 'Alcohol withdrawal promotes regression of pancreatic fibrosis via induction of pancreatic stellate cell (PSC) apoptosis', in Journal of Gastroenterology and Hepatology, Wiley, pp. A333 - A333, presented at AGW, - ,
    Conference Papers | 2009
    Xu Z; Phillips PA; Vonlaufen A; Fiala-Beer E; Yang L; Biankin AV; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Pancreatic stellate cells (stromal cells) migrate with pancreatic cancer cells to distant metastatic sites', in Journal of Gastroenterology and Hepatology, Wiley, pp. A334 - A335, presented at AGW, - ,
    Conference Papers | 2008
    Apte MV; Vonlaufen A; Xu ZH; Phillips PA; Parker N; Pirola RC; Wilson JS, 2008, 'Pancreatic stellate cells: Major players in alcoholic pancreatitis and pancreatic cancer', in Alcoholism : Clinical and Experimental Research, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 292A - 292A, presented at International-Society-for-Biomedical-Research-on-Alcoholism, Washington DC, USA, 27 June 2008 - 02 July 2008
    Conference Papers | 2008
    Phillips PA; Yang L; Vonlaufen A; Xu Z; Pirola R; Wilson JS; Apte MV, 2008, 'Heat shock proteins are differentially regulated during pancreatic stellate cell activation', in Pancreas, pp. 489 - 490, presented at American Pancreatic Association, - ,
    Conference Papers | 2008
    Phillips PA; Yang L; Vonlaufen A; Xu ZH; Pirola RC; Wilson JS; Apte MV, 2008, 'Heat shock proteins are differentially regulated during pancreatic stellate cell activation', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A308 - A308, presented at Journal of Gastroenterology and Hepatology
    Conference Papers | 2008
    Vonlaufen A; Xu Z; Phillips PA; Yang L; Zhang X; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Journal of Gastroenterology and Hepatology, Wiley, pp. A308 - A308,
    Conference Papers | 2008
    Vonlaufen A; Xu Z; Phillips PA; Yang L; Zhang X; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Pancreas, pp. 499 - 499, presented at American Pancreatic Association, - ,
    Conference Papers | 2008
    Vonlaufen A; Xu Z; Yang L; Phillips P; Zhang X; Pirola R; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-Induced pancreatic injury in alcohol-fed rats', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. A585 - A585,
    Conference Papers | 2008
    Vonlaufen A; Xu ZH; Phillips PA; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Alcoholism : Clinical and Experimental Research, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 223A - 223A, presented at International-Society-for-Biomedical-Research-on-Alcoholism, Washington DC, USA, 27 June 2008 - 02 July 2008
    Conference Papers | 2008
    Xu Z; Li Y; Rizos C; Xu X; Xu Z, 2008, 'Rapid Initialization of SINS for Land Vehicle-based Vertically-launched Missiles', in Proceedings of ION GNSS 2008, The Institute of Navigation (ION), Savannah, Georgia, USA, pp. 554 - 559, presented at 21st International Technical Meeting of the Satellite Division of the Institute of Navigation, Savannah, Georgia, USA, 16 September 2008 - 19 September 2008,
    Conference Papers | 2008
    Xu ZH; Vonlaufen A; Yang L; Phillips PA; Fiala-Beer E; Biankin AV; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2008, 'Pancreatic stellate cells stimulate angiogenesis in pancreatic cancer and accompany pancreatic cancer cells to distant metastatic sites', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 502 - 503, presented at Pancreas
    Conference Papers | 2007
    Xu Z; Vonlaufen A; Shulkes A; Pirola RC; Wilson JS; Apte MV, 2007, 'Do pancreatic stellate cells play a role in exocrine pancreatic secretion?', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A725 - A725, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007,
    Conference Papers | 2006
    Joshi SB; Vonlaufen A; Xu Z; Daniel B; Qu CF; Kumar RK; Pirola RC; Wilson JS; Goldstein D; Apte MV, 2006, 'Pancreatic stellate cells stimulate pancreatic cancer growth and metastasis: Findings of a novel orthotopic model of pancreatic cancer', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, -
    Conference Papers | 2006
    Vonlaufen A; Xu Z; Daniel B; Joshi SB; Kumar RK; Pirola RC; Wilson JS; Apte MV, 2006, 'Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model', in Pancreas, Lippincott Williams & Wilkins, pp. 506 - 507,
    Conference Papers | 2005
    Mazieres J; You L; He B; Xu Z; Reguart N; Batra S; Jablons D, 2005, 'Wnt2 as a new therapeutic target in malignant pleural mesothelioma', in LUNG CANCER, ELSEVIER IRELAND LTD, SPAIN, Barcelona, pp. S225 - S225, presented at 11th World Conference on Lung Cancer, SPAIN, Barcelona, 03 July 2005 - 06 July 2005,
    Conference Papers | 2004
    Xu Z; Feng YJ; Xia S; Wang D; Yao X, 2004, 'Pulse electric field induced phase transition behaviors of La-doped Pb(ZrSn,Ti)O-3 antiferroelectric ceramics', in Yuhas MP (ed.), 2004 14th IEEE International Symposium on Applications of Ferroelectrics-ISAF-04, IEEE, CANADA, Montreal, pp. 301 - 304, presented at 14th IEEE International Symposium on Applications of Ferroelectrics (ISAF-04), CANADA, Montreal, 23 August 2004 - 27 August 2004,
    Conference Papers | 2001
    Xu Z; Konercki G; Reed CB; Gahan BC; Parker RA; Batarseh S; Graves RM, 2001, 'Specific energy for laser removal of rocks', in 20TH ICALEO 2001, VOLS 92 & 93, CONGRESS PROCEEDINGS, LASER INST AMERICA, FL, JACKSONVILLE, pp. 87 - 95, presented at 20th International Congress on Applications of Lasers and Electro-Optics (ICALEO 2001), FL, JACKSONVILLE, 14 October 2001 - 18 October 2001,
    Conference Papers | 1999
    Qi L; Shen XP; Zou JZ; Hu HM; Huan XY; Xu Z, 1999, 'Synthesis, structure, and magnetic properties of [Mn(salen)H2O]6.Fe(CN)6.', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, pp. U857 - U857,
    Conference Papers | 1999
    Qi L; Suo ZY; Wei XW; Mei YH; Xu Z, 1999, 'Group transfer and dimerization processes of C-60(CN)(2) in gaseous phase.', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, pp. U842 - U842,
    Conference Papers | 1997
    Wang SW; Wei XW; Qi L; Xu Z, 1997, 'Synthesis and characterization of divalent organolanthanide-fullerene adducts Cp(2)LnC(60) (Ln=Yb, Sm): First example of insertion reaction involving cyclopentadienyl and fullerene.', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, pp. 238 - INOR,
    Conference Papers | 1997
    Wu MF; Wei XW; Qi L; Xu Z, 1997, 'The selective solution-phase generation of fullerene anions and the formation of an aqueous colloidal solution of fullerene.', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, pp. 239 - INOR,

1.ÌýÌýÌýÌýCo-investigatorÌýof National Health and Medical Research Council Ideas Grant.ÌýPancreatic Cancer-Related Diabetes: Novel Role of Pancreatic Stellate CellsÌý(2020Ìý–2023;Ìý$486,210).

2.ÌýÌýÌýÌýÌýLead ResearcherÌýof Tour de CureÌýof pancreatic cancer: Capture, investigate and target circulating stromal cells and cancer cells (2019; $80,000). Funded by Tour de Cure.

3.ÌýÌýÌýÌýÌýCo-investigatorÌýof Avner Pancreatic Cancer Foundation Accelerator Grant. Pathway to a Novel Treatment for Pancreatic Cancer – Targeting the Microenvironment (Stroma) (2018 – 2020; $735,815)

  • Basic Research Paper of the Year by the South West Sydney Clinical Campuses. Xu et al., Targeting the HGF/c-MET pathway in advanced pancreatic cancer: A key element of treatment that limits primary tumour growth and eliminates metastasis. Br J Cancer 2020 May; 122(10): 1486–1495.
  • Finalist of Young Investigator Award, Australian Gastroenterology Week 2019.ÌýXu Z., et al. Inhibition of Hepatocyte Growth Factor (HGF) Signalling Pathway in Combination with Chemotherapy Reduces Tumour Burden in an Orthotopic Model of Advanced Pancreatic Cancer.Ìý8-10 Sep 2019, Adelaide Convention Centre, Australia. ​
  • Young Investigator Travel Award for the 2018 the annual meeting of the American Pancreatic Association (APA), 31 Oct - 3 November 2018, Miami, Florida, USA. Ìý
  • Travel Award from International Association of Pancreatology (IAP) for the 2017 IAP and LAPSG Joint Meeting. 28-30 September 2017, Buenos Aires, Argentina. Ìý
  • Papers of the Year Biomedical Research (South Western Sydney Clinical School, Faculty of Medicine, Õ¬Äи£Àû Sydney). Lee*, Xu* et al (*Equal first authors). Alcohol and cigarette smoke components activate human pancreatic stellate cells: Implications for the progression of chronic pancreatitis.Alcoholism: Clinical and Experimental Research. Vol 39(11):2123-33. Ìý
  • Young Investigator Travel Award from IAP for the joint annual meeting of the Pancreatic Cancer Committee of Chinese Anti-Cancer Association and IAP, 27-29 August 2015, Shanghai, China. ÌýPaper of the Month Awards (School of Medical Sciences, Faculty of Medicine, Õ¬Äи£Àû Sydney): Xu et al, Role of pancreatic stellate cells in pancreatic cancer metastasis. Am J Patho, Vol 177 (5):2585-96.Ìý

My research interests focus on pancreatic cancer, chronic pancreatitis and the biology of pancreatic exocrine function.Ìý

My Research Supervision

Honours