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Dr Raymond Louie

Dr Raymond Louie

Lecturer
  • PhD. in Electrical Engineering, University of Sydney, Australia

  • B.E/B. Sc. in Electrical Engineering/Computer Science (1st Class Honours), University of New South Wales, Australia

Engineering
Computer Science and Engineering

I am a computational biologist and bioinformatician, with a current focus on applying machine learning and computational tools to analyze immune cells in patients with HCV, cealiac disease or blood malignancies treated with CAR T therapy.

I received a PhD in Electrical Engineering at the University of Sydney, after which I was an ARC Postdoctoral Fellow focusing on wireless communications. I then moved to the Hong Kong University of Science and Technology, where I focused on applying statistical and machine learning tools to viral sequence data, to aid in the design of effective vaccines. My background allows for a unique multi-disciplinary approach to solving biological problems.

I am currently recruiting PhD students. Please contact me if interested.

  • Journal articles | 2023
    Gupta M; Balachandran H; Louie RHY; Li H; Agapiou D; Keoshkerian E; Christ D; Rawlinson W; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Bartlett AW; Sasson SC; Ahlenstiel G; Dwyer D; Lloyd AR; Martinello M; Luciani F; Bull RA, 2023, 'High activation levels maintained in receptor-binding domain–specific memory B cells in people with severe coronavirus disease 2019', Immunology and Cell Biology, 101, pp. 142 - 155,
    Journal articles | 2023
    Louie RHY; Cai C; Samir J; Singh M; Deveson IW; Ferguson JM; Amos TG; McGuire HM; Gowrishankar K; Adikari T; Balderas R; Bonomi M; Ruella M; Bishop D; Gottlieb D; Blyth E; Micklethwaite K; Luciani F, 2023, 'CAR+ and CAR T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies', Nature Communications, 14,
    Journal articles | 2023
    Yang Y; Louie R; Puc J; Vedvyas Y; Alcaina Y; Min IM; Britz M; Luciani F; Jin MM, 2023, 'Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance', Cancers, 15,
    Journal articles | 2022
    Cai C; Samir J; Pirozyan MR; Adikari TN; Gupta M; Leung P; Hughes B; Van der Byl W; Rizzetto S; Elthala A; Keoshkerian E; Palgen JL; Peters T; Nguyen THO; Louie R; Kedzierska K; Gaudieri S; Bull RA; Lloyd AR; Luciani F, 2022, 'Identification of human progenitors of exhausted CD8+ T cells associated with elevated IFN-γ response in early phase of viral infection', Nature Communications, 13,
    Journal articles | 2022
    Sohail MS; Louie RHY; Hong Z; Barton JP; Mckay MR, 2022, 'Inferring Epistasis from Genetic Time-series Data', Molecular Biology and Evolution, 39,
    Journal articles | 2021
    Louie RHY; Luciani F, 2021, 'Recent advances in single-cell multimodal analysis to study immune cells', Immunology and Cell Biology, 99, pp. 157 - 167,
    Journal articles | 2021
    Micklethwaite KP; Gowrishankar K; Gloss BS; Li Z; Street JA; Moezzi L; Mach MA; Sutrave G; Clancy LE; Bishop DC; Louie RHY; Cai C; Foox J; MacKay M; Sedlazeck FJ; Blombery P; Mason CE; Luciani F; Gottlieb DJ; Blyth E, 2021, 'Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells', Blood, 138, pp. 1391 - 1405,
    Journal articles | 2021
    Sohail MS; Louie RHY; McKay MR; Barton JP, 2021, 'MPL resolves genetic linkage in fitness inference from complex evolutionary histories', Nature Biotechnology, 39, pp. 472 - 479,
    Journal articles | 2020
    Quadeer AA; McKay MR; Barton JP; Louie RHY, 2020, 'MPF-BML: A standalone GUI-based package for maximum entropy model inference', Bioinformatics, 36, pp. 2278 - 2279,
    Journal articles | 2019
    Quadeer AA; Louie RHY; McKay MR, 2019, 'Identifying immunologically-vulnerable regions of the HCV E2 glycoprotein and broadly neutralizing antibodies that target them', Nature Communications, 10,
    Journal articles | 2018
    Louie RHY; Kaczorowski KJ; Barton JP; Chakraborty AK; McKay MR, 2018, 'Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies', Proceedings of the National Academy of Sciences of the United States of America, 115, pp. E564 - E573,
    Journal articles | 2016
    Wu Y; Louie RHY; McKay MR, 2016, 'Asymptotic Outage Probability of MIMO-MRC Systems in Double-Correlated Rician Environments', IEEE Transactions on Wireless Communications, 15, pp. 367 - 376,
    Journal articles | 2015
    Morales-Jimenez D; Louie RHY; McKay MR; Chen Y, 2015, 'Analysis and Design of Multiple-Antenna Cognitive Radios with Multiple Primary User Signals', IEEE Transactions on Signal Processing, 63, pp. 4925 - 4939,
    Journal articles | 2014
    Bayat S; Louie RHY; Han Z; Vucetic B; Li Y, 2014, 'Distributed user association and femtocell allocation in heterogeneous wireless networks', IEEE Transactions on Communications, 62, pp. 3027 - 3043,
    Journal articles | 2014
    Chen H; Li Y; Louie RHY; Vucetic B, 2014, 'Autonomous demand side management based on energy consumption scheduling and instantaneous load billing: An aggregative game approach', IEEE Transactions on Smart Grid, 5, pp. 1744 - 1754,
    Journal articles | 2014
    Louie RHY; Hardjawana W; Li Y; Vucetic B, 2014, 'Distributed multiple-access for smart grid home area networks: Compressed sensing with multiple antennas', IEEE Transactions on Smart Grid, 5, pp. 2938 - 2946,
    Journal articles | 2014
    Quadeer AA; Louie RHY; Shekhar K; Chakraborty AK; Hsing IM; McKay MR, 2014, 'Statistical linkage analysis of substitutions in patient-derived sequences of genotype 1a Hepatitis C virus nonstructural protein 3 exposes targets for immunogen design', Journal of Virology, 88, pp. 7628 - 7644,
    Journal articles | 2013
    Bayat S; Louie RHY; Han Z; Vucetic B; Li Y, 2013, 'Physical-layer security in distributed wireless networks using matching theory', IEEE Transactions on Information Forensics and Security, 8, pp. 717 - 732,
    Journal articles | 2013
    Bayat S; Louie RHY; Vucetic B; Li Y, 2013, 'Dynamic decentralised algorithms for cognitive radio relay networks with multiple primary and secondary users utilising matching theory', Transactions on emerging telecommunications technologies, 24, pp. 486 - 502,
    Journal articles | 2013
    Wu Y; Louie RHY; McKay MR, 2013, 'Analysis and design of wireless ad hoc networks with channel estimation errors', IEEE Transactions on Signal Processing, 61, pp. 1447 - 1459,
    Journal articles | 2012
    Wu Y; Louie RHY; McKay MR; Collings IB, 2012, 'Generalized framework for the analysis of linear MIMO transmission schemes in decentralized wireless ad hoc networks', IEEE Transactions on Wireless Communications, 11, pp. 2815 - 2827,
    Journal articles | 2011
    Louie RHY; McKay MR; Collings IB, 2011, 'Open-loop spatial multiplexing and diversity communications in ad hoc networks', IEEE Transactions on Information Theory, 57, pp. 317 - 344,
    Journal articles | 2011
    Manna R; Louie RHY; Li Y; Vucetic B, 2011, 'Cooperative spectrum sharing in cognitive radio networks with multiple antennas', IEEE Transactions on Signal Processing, 59, pp. 5509 - 5522,
    Journal articles | 2010
    Elkashlan M; Yeoh PL; Louie RHY; Collings IB, 2010, 'On the exact and asymptotic ser of receive diversity with multiple amplify-and-forward relays', IEEE Transactions on Vehicular Technology, 59, pp. 4602 - 4608,
    Journal articles | 2010
    Li Y; Louie RHY; Vucetic B, 2010, 'Relay selection with network coding in two-way relay channels', IEEE Transactions on Vehicular Technology, 59, pp. 4489 - 4499,
    Journal articles | 2010
    Louie RHY; Li Y; Vucetic B, 2010, 'Practical physical layer network coding for two-way relay channels: Performance analysis and comparison', IEEE Transactions on Wireless Communications, 9, pp. 764 - 777,
    Journal articles | 2010
    Louie RHY; Li Y; Vucetic B, 2010, 'Zero forcing in general two-hop relay networks', IEEE Transactions on Vehicular Technology, 59, pp. 191 - 202,
    Journal articles | 2009
    Louie RHY; Li Y; Suraweera HA; Vucetic B, 2009, 'Performance analysis of beamforming in two hop amplify and forward relay networks with antenna correlation', IEEE Transactions on Wireless Communications, 8, pp. 3132 - 3141,
    Journal articles | 2009
    Louie RHY; McKay MR; Collings IB, 2009, 'Maximum sum-rate of mimo multiuser scheduling with linear receivers', IEEE Transactions on Communications, 57, pp. 3500 - 3510,
    Journal articles | 2009
    Louie RHY; McKay MR; Collings IB, 2009, 'New performance results for multiuser optimum combining in the presence of rician fading', IEEE Transactions on Communications, 57, pp. 2348 - 2358,
    Journal articles | 2009
    Suraweera HA; Louie RHY; Li Y; Karagiannidis GK; Vucetic B, 2009, 'Two hop amplify-and-forward transmission in mixed Rayleigh and Rician fading channels', IEEE Communications Letters, 13, pp. 227 - 229,
    Journal articles | 2008
    Louie RHY; McKay MR; Collings TB, 2008, 'Impact of correlation on the capacity of multiple access and broadcast channels with MIMO-MRC', IEEE Transactions on Wireless Communications, 7, pp. 2397 - 2407,
  • Preprints | 2024
    Singh M; Louie RHY; Samir J; Field MA; Milthorpe C; Aldiriki T; Mackie J; Roper E; Faulks M; Jackson KJL; Calcino A; Hardy MY; Blombery P; Amos TG; Deveson IW; Read SA; Shek D; Guerin A; Ma CS; Tangye SG; Sabatino AD; Lenti MV; Pasini A; Ciccocioppo R; Ahlenstiel G; Suan D; Tye-Din JA; Goodnow CC; Luciani F, 2024, Expanded T cell clones with lymphoma driver somatic mutations in refractory celiac disease, ,
    Preprints | 2022
    Louie RHY; Cai C; Singh M; Deveson I; Ferguson J; Amos T; McGuire HM; Samir J; Gowrishankar K; Adikari T; Balderas R; Bishop D; Gottlieb D; Blyth E; Micklethwaite K; Luciani F, 2022, CAR+ and CAR- T cells differentiate into an NK-like subset that is associated with increased inflammatory cytokines following infusion, ,
    Conference Papers | 2021
    Adikari TN; Singh M; Munier ML; Louie R; Samir J; Balraj V; Cai C; Hardy MY; John JR; Reid H; Kelleher AD; Din JAT; Goodnow C; Luciani F, 2021, 'Single cell RNA sequencing of gluten-specific CD4+T cells reveals a novel gene expression pattern with NK-like cytotoxicity', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, pp. 96 - 96,
    Preprints | 2021
    Cai C; Samir J; Pirozyan M; Adikari T; Gupta M; Leung P; Hughes B; Van der Byl W; Rizzetto S; Elthala A; Keoshkerian E; Palgen J-L; Peters T; Nguyen T; Louie R; Kedzierska K; Gaudieri S; Bull R; Lloyd A; Luciani F, 2021, Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8+ T cells, ,
    Conference Papers | 2021
    Louie R; Cai C; Balraj V; Singh M; Jackson K; Deveson I; Ferguson J; Amos T; Gowrishankar K; Bishop D; Blyth E; Gottlieb D; Micklethwaite K; Luciani F, 2021, 'Single cell multi-omics identifies evolving phenotypes of CAR CD19 and endogenous T cell clones', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, pp. 412 - 412,
    Preprints | 2019
    Sohail M; Louie R; McKay M; Barton J, 2019, Resolving genetic linkage reveals patterns of selection in HIV-1 evolution, ,
    Conference Papers | 2014
    Louie RHY; McKay MR; Chen Y, 2014, 'Multiple-antenna signal detection in cognitive radio networks with multiple primary user signals', in 2014 IEEE International Conference on Communications, ICC 2014, pp. 4951 - 4956,
    Preprints | 2014
    Morales-Jimenez D; Louie RHY; McKay MR; Chen Y, 2014, Analysis and Design of Multiple-Antenna Cognitive Radios with Multiple Primary User Signals, ,
    Conference Papers | 2014
    Quadeer AA; Louie RHY; Shekhar K; Chakraborty AK; Hsing I; McKay MR, 2014, 'Discovering statistical vulnerabilities in highly mutable viruses: A random matrix approach', in IEEE Workshop on Statistical Signal Processing Proceedings, pp. 5 - 8,
    Conference Papers | 2014
    Zhu J; Louie RHY; McKay MR; Govindasamy S, 2014, 'On the impact of unsynchronized interferers on multi-antenna OFDM systems', in 2014 IEEE International Conference on Communications, ICC 2014, pp. 2203 - 2208,
    Preprints | 2013
    Chen H; Li Y; Louie RHY; Vucetic B, 2013, Autonomous Demand Side Management Based on Energy Consumption Scheduling and Instantaneous Load Billing: An Aggregative Game Approach, ,
    Conference Papers | 2013
    Chen HH; Louie RHY; Li Y; Wang P; Vucetic B, 2013, 'A variational inequality approach to instantaneous load pricing based demand side management for future smart grid', in IEEE International Conference on Communications, pp. 4250 - 4254,
    Conference Papers | 2013
    Wu Y; Louie RHY; McKay MR, 2013, 'Impact of training on multiple-antenna communications in wireless ad hoc networks', in Conference Record - Asilomar Conference on Signals, Systems and Computers, pp. 1324 - 1329,
    Conference Papers | 2012
    Bayat S; Louie RHY; Han Z; Li Y; Vucetic B, 2012, 'Distributed stable matching algorithm for physical layer security with multiple source-destination pairs and jammer nodes', in IEEE Wireless Communications and Networking Conference, WCNC, pp. 2688 - 2693,
    Conference Papers | 2012
    Bayat S; Louie RHY; Han Z; Li Y; Vucetic B, 2012, 'Multiple operator and multiple femtocell networks: Distributed stable matching', in IEEE International Conference on Communications, pp. 5140 - 5145,
    Conference Papers | 2012
    Bayat S; Louie RHY; Li Y; Ng SX; Vucetic B, 2012, 'Distributed algorithm for multiple antenna cooperative cognitive radio networks with multiple primary and secondary users', in Progress in Electromagnetics Research Symposium, pp. 297 - 302
    Conference Papers | 2012
    Louie RHY; Hardjawana W; Li Y; Vucetic B, 2012, 'Distributed multiple-access for wireless communications: Compressed sensing with multiple antennas', in Proceedings - IEEE Global Communications Conference, GLOBECOM, pp. 3622 - 3627,
    Conference Papers | 2012
    Wu Y; Louie RHY; McKay MR, 2012, 'Impact of training on the transmission capacity of wireless ad hoc networks', in ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, pp. 3133 - 3136,
    Conference Papers | 2011
    Bayat S; Louie RHY; Li Y; Vucetic B, 2011, 'Cognitive radio relay networks with multiple primary and secondary users: Distributed stable matching algorithms for spectrum access', in IEEE International Conference on Communications,
    Preprints | 2011
    Bayat S; Louie RHY; Vucetic B; Li Y, 2011, Dynamic Decentralized Algorithms for Cognitive Radio Relay Networks, ,
    Conference Papers | 2011
    Louie RHY; McKay MR; Jindal N; Collings IB, 2011, 'Spatial multiplexing with MMSE receivers in ad hoc networks', in IEEE International Conference on Communications,
    Conference Papers | 2010
    Elkashlan M; Yeoh PL; Louie RHY; Collings IB, 2010, 'Exact and asymptotic SER of receive diversity in multiple amplify-and-forward relaying', in IEEE International Conference on Communications,
    Conference Papers | 2010
    Elkashlan M; Yeoh PL; Louie RHY; Collings IB, 2010, 'SER of multiple fixed gain amplify-and-forward relays with receive diversity', in IEEE Vehicular Technology Conference,
    Preprints | 2010
    Li Y; Louie RHY; Vucetic B, 2010, Relay Selection with Network Coding in Two-Way Relay Channels, ,
    Preprints | 2010
    Louie RHY; McKay MR; Collings IB, 2010, Open-Loop Spatial Multiplexing and Diversity Communications in Ad Hoc Networks, ,
    Preprints | 2010
    Louie RHY; McKay MR; Jindal N; Collings IB, 2010, Spatial multiplexing with MMSE receivers: Single-stream optimality in ad hoc networks, ,
    Conference Papers | 2010
    Manna R; Louie RHY; Li Y; Vucetic B, 2010, 'Cooperative amplify-and-forward relaying in cognitive radio networks', in 2010 Proceedings of the 5th International Conference on Cognitive Radio Oriented Wireless Networks and Communications, CROWNCom 2010,
    Conference Papers | 2010
    Manna R; Louie RHY; Li Y; Vucetic B, 2010, 'Interference cancellation in two hop multiuser cognitive radio networks', in IEEE Wireless Communications and Networking Conference, WCNC,
    Conference Papers | 2010
    Wu Y; Louie RHY; McKay MR; Collings IB, 2010, 'Benefits of transmit antenna selection in ad hoc networks', in GLOBECOM - IEEE Global Telecommunications Conference,
    Conference Papers | 2010
    Wu Y; Louie RHY; McKay MR; Collings IB, 2010, 'MIMO beamforming with quantized feedback in ad hoc networks: Transmission capacity analysis', in Conference Record - Asilomar Conference on Signals, Systems and Computers, pp. 1582 - 1587,
    Conference Papers | 2009
    Louie RHY; Li Y; Suraweera HA; Vucetic B, 2009, 'Beamforming with Antenna Correlation in Two Hop Amplify and Forward Relay Networks', in 2009 IEEE WIRELESS COMMUNICATIONS & NETWORKING CONFERENCE, VOLS 1-5, IEEE, HUNGARY, Budapest, pp. 7 - +, presented at IEEE Wireless Communications and Networking Conference, HUNGARY, Budapest, 05 April 2009 - 08 April 2009,
    Conference Papers | 2009
    Louie RHY; Li Y; Suraweera HA; Vucetic B, 2009, 'Beamforming with antenna correlation in two hop amplify and forward relay networks', in IEEE Wireless Communications and Networking Conference, WCNC,
    Conference Papers | 2009
    Louie RHY; Li Y; Vucetic B, 2009, 'Performance Analysis of Physical Layer Network Coding in Two-Way Relay Channels', in Ulema M (ed.), GLOBECOM 2009 - 2009 IEEE GLOBAL TELECOMMUNICATIONS CONFERENCE, VOLS 1-8, IEEE, HI, Honolulu, pp. 2242 - 2247, presented at IEEE Global Telecommunications Conference (GLOBECOM 09), HI, Honolulu, 30 November 2009 - 04 December 2009,
    Conference Papers | 2009
    Louie RHY; Li Y; Vucetic B, 2009, 'Performance analysis of physical layer network coding in two-way relay channels', in GLOBECOM - IEEE Global Telecommunications Conference,
    Conference Papers | 2009
    Louie RHY; Li Y; Vucetic B, 2009, 'Zero Forcing Processing in Two Hop Networks with Multiple Source, Relay and Destination Nodes', in 2009 IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS, VOLS 1-8, IEEE, GERMANY, Dresden, pp. 3983 - 3987, presented at IEEE International Conference on Communications (ICC 2009), GERMANY, Dresden, 14 June 2009 - 18 June 2009,
    Conference Papers | 2009
    Louie RHY; Li Y; Vucetic B, 2009, 'Zero forcing processing in two hop networks with multiple source, relay and destination nodes', in IEEE International Conference on Communications,
    Conference Papers | 2009
    Louie RHY; McKay MR; Collings IB, 2009, 'Spatial Multiplexing with MRC and ZF Receivers in Ad Hoc Networks', in 2009 IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS, VOLS 1-8, IEEE, GERMANY, Dresden, pp. 1627 - +, presented at IEEE International Conference on Communications (ICC 2009), GERMANY, Dresden, 14 June 2009 - 18 June 2009,
    Conference Papers | 2009
    Louie RHY; McKay MR; Collings IB, 2009, 'Spatial multiplexing with MRC and ZF receivers in ad hoc networks', in IEEE International Conference on Communications,
    Conference Papers | 2008
    Louie RHY; Li Y; Vucetic B, 2008, 'Performance analysis of beamforming in two hop amplify and forward relay networks', in IEEE International Conference on Communications, pp. 4311 - 4315,
    Conference Papers | 2008
    Louie RHY; McKay MR; Collings IB, 2008, 'New asymptotic performance results for MIMO and SIMO optimum combining', in Proceedings of the 2008 Australian Communications Theory Workshop, AusCTW08, pp. 69 - 74,
    Conference Papers | 2008
    Louie RHY; McKay MR; Collings IB, 2008, 'On the use of multiple antennas to reduce MAC layer coordination in Ad hoc networks', in IEEE International Conference on Communications, pp. 4554 - 4558,
    Conference Papers | 2008
    Louie RHY; McKay MR; Collings IB, 2008, 'Optimum combining in Rician fading: Performance analysis in asymptotic SNR regimes', in IEEE International Conference on Communications, pp. 850 - 854,
    Conference Papers | 2008
    Louie RHY; McKay MR; Collings IB, 2008, 'Sum Capacity of Opportunistic Scheduling for Multiuser MIMO Systems with Linear Receivers', in GLOBECOM - IEEE Global Telecommunications Conference, pp. 3724 - 3728,
    Conference Papers | 2008
    Louie RHY; McKay MR; Collings IB, 2008, 'optimum combining systems in the presence of Rician fading: SINR and capacity analysis', in ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, pp. 2745 - 2748,
    Preprints | 2008
    Louie RHY; McKay MR; Collings IB, 2008, Maximum Sum-Rate of MIMO Multiuser Scheduling with Linear Receivers, ,
    Conference Papers | 2007
    Louie RHY; Collings IB; McKay MR, 2007, 'Analysis of dense ad hoc networks with spatial diversity', in GLOBECOM - IEEE Global Telecommunications Conference, pp. 1253 - 1257,
    Conference Papers | 2007
    Louie RHY; McKay MR; Collings IB; Vucetic B, 2007, 'Capacity approximations for multiuser MIMO-MRC with antenna correlation', in IEEE International Conference on Communications, pp. 5195 - 5200,
    Conference Papers | 2007
    Louie RHY; McKay MR; Collings IB, 2007, 'Capacity increase with antenna correlation for multiuser MIMO-MRC', in 8th Australian Communication Theory Workshop, AusCTW 2007, pp. 139 - 143

  • NHMRC Ideas Grant CIB (2024-2027)

    • "Harnessing Pathogenic Immune Cells to Develop a New Diagnostic for Non-Responders and Refractory Conditions in Celiac Disease", AUD $1,094,640.50.

  • Hong Kong Research Grants Council General Research Fund, Chief  (Primary) Investigator (2017-2019)

    • “Statistical inference of the fitness parameters driving viral evolution using time series data”, HKD 482,605 (AUD 77,168.32)

  • Hong Kong Research Grants Council General Research Fund, Chief (Primary) Investigator (2016-2018),

    • A novel statistical inference framework for big data applications: Identifying hidden multi-variate non-linear associations”, HKD 696,029 (AUD 111,294.72)

  • Australian Research Council Discovery Project grant, Chief (and sole) Investigator (2011-2013). 

    • Design of future cognitive radio relay networks”. AUD 255,000 

Rational vaccine design using computational models: The past few years has seen an abundance in sequence data for viruses such as SARS-CoV-2, HIV and HCV. This information can be exploited for the rational design of vaccines, by building models which capture the patterns in the viral sequences. These patterns can be exploited to find weaknesses in the virus, which can then be used to design effective vaccines.

Developing a machine learning model to predict disease outcome: Accurately predicting disease outcomes can have a significant impact on patient care, leading to early detection, personalized treatment plans, and improved clinical outcomes. Machine learning algorithms provide a powerful tool to achieve this goal by identifying novel biomarkers and drug targets for various diseases. By integrating machine learning algorithms with biological data, you will have the opportunity to push the boundaries of precision medicine and contribute to algorithms that can revolutionize the field. Such biological data includes single-cell datasets, where we have considerable experience.

My Teaching

  • BINF3010 Applied Bioinformatics (լи)
    • T2 2023 (lecturer in charge)
  • BINF3020 Computational Bioinformatics (լи)
    • T3 2023 (guest lecturer)
  • ENG1811 Computing for Engineers (լи)
    • T2 2023 (co-teaching)
  • ELEC2100H Honors – Signals and Systems (HKUST)
    • Fall 2015, 2016, 2017 (full course)
  • ELEC5450 – Random Matrix Theory and Applications (HKUST)
    • 8/3/2017, 15/3/2017, 16/3/2018 (guest lecturer)
  • BIEN5040 – Introduction to Bioengineering Research (HKUST)
    • 23/9/2015, 30/9/2015, 7/10/2016 (guest lecturer)
  • ELEC2600 - Probability and Random Processes in Engineering (HKUST)
    • Fall 2014 (full course)
    • 8/11/2013 (guest lecturer)
  • ELEC5507 – Error Control Coding (University of Sydney)
    • 2010-2012 (full course)